Covaxin v/s Covishield – A Detailed Comparison – Efficacy, Side effects

As the Covid-19 pandemic erupts globally, India has two regionally manufactured vaccines to battle the deadly virus, Covishield and Covaxin.

Covaxin or Covishield | Health Script
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Covaxin and Covishield are the initial vaccines authorized for use in India.

Covishield has developed by the Oxford-AstraZeneca and fabricated by the Serum Institute of India (SII). It is a viral vector vaccine, a strain from chimpanzees comprising the virus protein that commonly causes cold. It does not let COVID-19 enter and trains the immune system to develop a will against it.

Covishield has been granted recognition as an emergency dose in Bulgaria, Germany, France, Iceland, Austria, Spain, Switzerland, and Sweden.

On the other hand, Covaxin is developed by the Bharat Biotech associated with the Indian Council of Medical Research (ICMR). It is an inactivated vaccine that has a deadly virus, which activates the immune response.

Covaxin has been granted recognition as an emergency dose in many countries, some of which are Zimbabwe, Guatemala, Mexico, Iran, Botswana, and the Philippines.

The World Health Organization (WHO) has not given any form of approval as of now.

The national drugs regulator’s committee approved Covaxin as an emergency dose for children aged 2-18 as protection against coronavirus.

WHO had received crucial documents expected from the Bharat Biotech further, required documents will be presented shortly. The phase 3 trial outcomes could help in procuring the approval.

Everything there is to know about Covishield and Covaxin:

 CovaxinCovishield
Shots DurationThe interim between the 2 doses is 4-6 weeks.The interim between 1st and 2nd doses is 12-16 weeks.
Efficacy RateThis     vaccine    can    be     78-95% effective after the other dose.Efficiency following another dose can fluctuate from 70-90%.
AgeAbove 18Above 18

How Covishield and Covaxin Works:

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Covishield vaccine induces the immune system in the human body to start producing antibodies. The interim among both the doses, first and second doses of Covishield is 12-16 weeks. Earlier, it was 4-6 weeks, but the interval has been extended due to the efficiency variations.

Covaxin is made by dead viruses, the body’s immune responses can, however, identify the deadly virus which further, stimulates the immune system to make required antibodies. The interim among both the doses, first and second doses of Covaxin is 4-6 weeks.

Efficacy of Covishield & Covaxin Vaccine

Covishield vaccine has a 70-90% effectual rate given by the Drug Controller General of India (DCGI). It delivers efficiently against the old strains but works well on the UK strain.

Covishield may be a reliable choice to prevent the Delta variant, further for those who have prior recovered and need to get jabbed.

Covaxin has a 78-95% of the effectual rate. It can induce antibodies that can counteract severe strains including the UK strain.

The Bharat Biotech stated that Covaxin has a 65% efficacy rate facing the delta variant. To be precise let’s briefly talk about the phase 3 trial.

The Phase 3 trial:

● The Phase 3 trial included 25,800 people.

● Around 2,433 people were above 60, whereas 4,500 people with medical infirmities.

● The trial discovered that Covaxin has an efficiency of 93.4% against critical COVID-19 complications.

● The efficiency of doses to the symptomatic virus was 77.8% as authenticated by PCR tests.

● The efficiency of doses to the asymptomatic virus was 63.6%.

Side Effects of Covisheild & Covaxin

Covishield

No precise data are backing this up but, is generally experienced by the majority of people:

● You may feel pain around the jabbed arm.

● You may have headaches.

● May feel feverish.

● Lack of appetite.

● Itching may be a common symptom.

● Swelling.

● Nausea.

● A lump at the injection site

Some people may face uncommon symptoms.

People may experience viral flu-like symptoms that are fever and body aches. You should not overlook if these symptoms.

People who have been affected by coronavirus before getting jabbed are reported to have this one rare side effect, runny nose.

 Covaxin

There is no definite information as such about it yet but commonly faced by people out there:

● Swelling and stiffness around the arm.

● May feel dizzy and weak.

● Difficulty in breathing.

● Allergic reaction.

● Nausea.

● Fatigue.

● Fever and headache.

These could be some of the mild symptoms upon getting jabbed but not just ignore if severe.

The Bottom Line

The government would not let people choose which vaccine they desire to get. However, the result of the phases suggests that both vaccines are safe and effective.

If you are wondering which is more reliable (Covaxin or Covishield), then the quick answer is all of the two.

Both are different in production and working, but developed to help us fight the virus. There are tiny variations among their effectiveness and, the result is to stabilize your immune system against the coronavirus.

Ultimately, that one important thing is that we protect ourselves and those around us by getting jabbed.

SOURCES

https://timesofindia.indiatimes.com/life-style/health-fitness/health-news/coronavirus-vaccinat ion-as-the-delta-variant-surges-experts-say-this-vaccine-might-be-the-most-protective-right-n ow/photostory/85069170.cms?picid=85069204

https://economictimes.indiatimes.com/industry/healthcare/biotech/bharat-biotech-claims-77-8

-efficacy-of-covaxin-in-phase-3-trials/articleshow/84085564.cms?from=mdr

https://www.livemint.com/news/india/covaxin-75-mn-doses-supplied-more-in-pipeline-vacci ne-65-effective-against-delta-variant-says-bharat-biotech-11628780802978.html

https://www.hindustantimes.com/india-news/bharat-biotech-s-covaxin-approved-for-emergen cy-use-in-children-101634029754231.html

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